Immunization with Skin Isografts Taken from Tolerant Mice
Author:
- 6 October 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 158 (3797) , 127-129
Abstract
Skin isografts from mice that were immunologically tolerant to allogeneic tissue had the ability to immunize isogeneic recipients against subsequent skin allografts. The immunizing isografts showed no gross signs of rejection themselves and appeared to be only the vehicles for transplantation antigen. It seems likely that allogeneic leukocytes derived from the spleen and bone marrow cells used to confer tolerance were contained in the skin of the tolerant mice and were transferred by the skin isografts in sufficient numbers to stimulate transplantation immunity.Keywords
This publication has 11 references indexed in Scilit:
- REJECTION OF MOUSE AUTOGRAFTS WITH A PURIFIED ALLOGENEIC RNAAnnals of the New York Academy of Sciences, 1966
- PROLONGATION OF RABBIT SKIN ALLOGRAFT SURVIVAL BY INFUSION OF SUBCELLULAR TRANSPLANTATION ANTIGEN*Annals of the New York Academy of Sciences, 1966
- Further Study on Chimerism in Tolerant Mice.Experimental Biology and Medicine, 1966
- Lymphocyte Transformation in Epithelium2JNCI: Journal of the National Cancer Institute, 1965
- Rejection of Isogeneic Murine Skin Grafts following Exposure to Allogeneic Ribonucleic AcidNature, 1964
- A TRANSPLANTATION ANTIGEN RECOVERED FROM CELL CULTURE MEDIUMTransplantation, 1964
- Some factors that determine the ability of cellular inocula to induce tolerance of tissue homograftsJournal of Cellular and Comparative Physiology, 1962
- Lymphocytes in the normal epidermis of the rat and of manThe Anatomical Record, 1949
- Behavior of Thymus Tissue Transplanted to a Skin WoundJNCI: Journal of the National Cancer Institute, 1945
- RELATION OF BLOOD CELLS TO CONNECTIVE TISSUES AND ENDOTHELIUMPhysiological Reviews, 1924