Cholic acid binding by glutathione S-transferases from rat liver cytosol
Authors:
- J D HayesJHJ D Hayes
- R C StrangeRSR C Strange
- I W Percy-RobbIPI W Percy-Robb
- 1 January 1980
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 185 (1) , 83-87
Abstract
Cholic acid-binding activity in cytosol from rat livers appears to be mainly associated with enzymes having glutathione S-transferase activity; at least four of the enzymes in this group can bind the bile acid. Examination of the subunit compositions of different glutathione S-transferases indicated that cholic acid binding and the ability to conjugate reduced glutathione with 1,2-dichloro-4-nitrobenzene may be ascribed to different subunits.Keywords
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