Essential oils and low-intensity electromagnetic pulses in the treatment of androgen-dependent alopecia
Authors:
- P. GinouvesPGP. Ginouves
- J. GuilbaudJGJ. Guilbaud
- 1 July 2003
- journal article
- clinical trial
- Published by Springer Nature in Advances in Therapy
- Vol. 20 (4) , 220-229
Abstract
This double-blind randomized study vs placebo in healthy male and female volunteers demonstrates the positive biologic effect on hair loss and hair regrowth of a pulsed electromagnetic field in combination with essential oils administered according to a regular treatment schedule of 26 weeks. Mean hair count comparisons within the groups significantly favor the treatment group, which exhibited a decrease in hair loss in 83% of the volunteers and a more than 20% hair count increase over baseline in 53% of patients. The process exhibited no side effects or untoward reactions. The histologic examination correlated with the clinical study. A parallel immunohistochemical examination showed an increase in the proliferation index, and when the expression of Ki67 (a cell proliferation marker) is increased, the mitoses are barely visible in the histologic examination. The rationale of this phenomenon is considered to be due to an electrophysiologic effect on the quiescent hair follicle.Keywords
This publication has 15 references indexed in Scilit:
- Relationship between the presence of oncogenic HPV DNA assessed by polymerase chain reaction and Ki‐67 immunoquantitative features in cervical intraepithelial neoplasiaThe Journal of Pathology, 2001
- The Phototrichogram: Analysis of Some Technical Factors of VariationSkin Pharmacology and Physiology, 1994
- ELECTROTRICHOGENESIS: FURTHER EVIDENCE OF EFFICACY AND SAFETY ON EXTENDED USEInternational Journal of Dermatology, 1992
- Natural progression of male pattern baldness in young menClinical and Experimental Dermatology, 1991
- The Biological Effects of a Pulsed Electrostatic Field with Specific Reference to Hair ElectrotrichogenesisInternational Journal of Dermatology, 1990
- Electric stimulation of human fibroblasts causes an increase in Ca2+ influx and the exposure of additional insulin receptorsJournal of Cellular Physiology, 1989
- ACCELERATED HEALING OF SKIN ULCERS BY ELECTRICAL STIMULATION AND THE INTRACELLULAR PHYSIOLOGICAL MECHANISMS INVOLVEDAcupuncture & Electro-Therapeutics Research: International Journal of Integrated Medicine, 1989
- The responses of cells to electrical fields: a review.Journal of Cell Biology, 1985
- Electromagnetic fields in biological studiesAnnals of Biomedical Engineering, 1985
- The Healing of Superficial Skin Wounds Is Stimulated by External Electrical CurrentJournal of Investigative Dermatology, 1983