Establishment and characteristics of two unique cell lines from patients with lymphosarcoma

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Abstract
Two human cell lines, U‐698 M and U‐715 M, with unique characteristics were derived from two patients with lymphosarcoma. The presented morphological and functional characteristics closely resemble those of lymphosarcoma cells in short‐term culture and also distinguish both lines from Epstein‐Barr virus‐carrying lymphoblastoid lines obtainable from normal and malignant lymphoid tissue. It is therefore proposed that the lines originate from the donors' tumor‐cell population.

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