A continuous kinetic assay for adenylation enzyme activity and inhibition

This publication has 38 references indexed in Scilit:

• Conformational Dynamics in the Acyl-CoA Synthetases, Adenylation Domains of Non-ribosomal Peptide Synthetases, and Firefly Luciferase
  ACS Chemical Biology, 2009
• DNA Ligases: Progress and Prospects
  Journal of Biological Chemistry, 2009
• Adenylation Enzyme Characterization Using γ -18O4-ATP Pyrophosphate Exchange
  Chemistry & Biology, 2009
• Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways
  Nature Reviews Molecular Cell Biology, 2009
• Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis
  Nature Chemical Biology, 2009
• Aryl Acid Adenylating Enzymes Involved in Siderophore Biosynthesis: Fluorescence Polarization Assay, Ligand Specificity, and Discovery of Non-nucleoside Inhibitors via High-Throughput Screening
  Biochemistry, 2008
• Inhibition of Siderophore Biosynthesis in Mycobacterium tuberculosis with Nucleoside Bisubstrate Analogues: Structure−Activity Relationships of the Nucleobase Domain of 5′-O-[N-(Salicyl)sulfamoyl]adenosine
  Journal of Medicinal Chemistry, 2008
• 5‘-O-[(N-Acyl)sulfamoyl]adenosines as Antitubercular Agents that Inhibit MbtA: An Adenylation Enzyme Required for Siderophore Biosynthesis of the Mycobactins
  Journal of Medicinal Chemistry, 2007
• Antitubercular Nucleosides That Inhibit Siderophore Biosynthesis: SAR of the Glycosyl Domain
  Journal of Medicinal Chemistry, 2006
• Protein production by auto-induction in high-density shaking cultures
  Protein Expression and Purification, 2005