Abstract
Much of the progress in the developing field of hepatocellular carcinoma (HCC) depends on general progress in oncology, on many non‐cancer‐related areas such as antiviral therapeutics and treatment of chronic liver disease, and on public health initiatives. It would therefore be inappropriate to make predictions in this field for the very near future, i.e. the next 1–2 years, and it would be difficult for the distant future of 100 years and beyond. The aim of this article is to survey the current status of the field and, on the basis of current knowledge, to make predictions for the next decade. Five facets of HCC are identified that impact on future directions in the management of the disease: epidemiology, prevention, screening, diagnosis and therapy.

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