Analyte-induced formation of partial duplexes for the preparation of a label-free electrochemiluminescent aptasensor
Authors:
- 9 May 2011
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 47 (22) , 6419-6421
Abstract
Analyte-induced formation of partial duplexes was used for biosensor development with cocaine as a model. The cocaine–aptamer interaction resulted in formation of a partial double strand section in the aptamer, where Ru(phen)3 2+ was intercalated for electrochemiluminescent analysis of cocaine.Keywords
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