BHT-derived thiazolidin-4-ones: synthesis, radical scavenging activity, and in silico evaluation
- 22 October 2026
- journal article
- Published by Royal Society of Chemistry (RSC) in RSC Medicinal Chemistry
- Vol. 17 (10) , 4888-4912
Abstract
BHT-functionalized thiazolidin-4-ones were synthesized via multicomponent strategies, with N-3 substitution influencing antioxidant activity. Compounds 4a, 4b, and 4d showed consistent radical-scavenging and oxidative stress protection.Keywords
Funding Information
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (309991/2022-6)
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (001)
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