Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Authors:
  • MCMary Jo Caranfa
    Mary Jo Caranfa
  • KHKenneth G. Holden
    Kenneth G. Holden
  • DJDalia R. Jakas
    Dalia R. Jakas
  • GGGregory Gallagher
    Gregory Gallagher
  • MMMichael R. Mattern
    Michael R. Mattern
  • SMShau Ming Mong
    Shau Ming Mong
  • JBJoan O'Leary Bartus
    Joan O'Leary Bartus
  • RJRandall K. Johnson
    Randall K. Johnson
  • WKWilliam D. Kingsbury
    William D. Kingsbury

Abstract
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