Single-molecule detection of amino acid phosphorylation using electron tunnelling currents: toward neurodegenerative disease diagnosis
Open Access
- 29 April 2026
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Nanoscale
- Vol. 18 (21) , 11453-11461
Abstract
Electrical single-molecule detection distinguishes all phosphorylated and non-phosphorylated Ser, Thr and Tyr, revealing the conductance mechanism underlying phosphorylation.Keywords
Funding Information
- Ministry of Education, Culture, Sports, Science and Technology (24K08201)
- Ministry of Education, Culture, Sports, Science and Technology (23K21064)
- Ministry of Education, Culture, Sports, Science and Technology (25H01060)
- Ministry of Education, Culture, Sports, Science and Technology (24K10680)
- Japan Science and Technology Corporation (JPMJKP23H3)
- Japan Science and Technology Corporation (K program JPMJKP23H3)
- Human Frontier Science Program (RGEC27/2023)
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