Abstract
Hydrogen peroxide (H2O2) is a central modulator of stomatal closure. It remains unknown, however, how the upstream regulation of H2O2 homeostasis operates. In this issue of Genes & Development, Huang and colleagues (pp. 1805–1817) report that a novel C2H2-type transcription factor, drought and salt tolerance (DST), mediates H2O2-induced stomatal closure and abiotic stress tolerance.

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