Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP
Authors:
- 1 August 1986
- journal article
- research article
- Published by Elsevier in Life Sciences
- Vol. 39 (7) , 581-588
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridineLife Sciences, 1985
- Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomesBiochemical and Biophysical Research Communications, 1985
- Reversible inhibition and mechanism-based irreversible inactivation of monoamine oxidases by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Biochemical and Biophysical Research Communications, 1985
- V. Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Life Sciences, 1985
- II. Selective accumulation of MPP+ in the substantia nigra: A key to neurotoxicity?Life Sciences, 1985
- Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTPBiochemical and Biophysical Research Communications, 1984
- Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidaseBiochemical and Biophysical Research Communications, 1984
- Monkey Model of Parkinson's DiseaseScience, 1983
- Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog SynthesisScience, 1983
- Studies on the electron transfer system IV. The electron transfer particleBiochimica et Biophysica Acta, 1956