Contrast enhanced CT scan and radionuclide brain scan in supratentorial gliomas

Authors:
  • ABAr Butler
    Ar Butler
  • APAm Passalaqua
    Am Passalaqua
  • ABA Berenstein
    A Berenstein
  • KRKricheff
    Kricheff
  • ABAm Passalaqua Ar Butler
    Am Passalaqua Ar Butler
  • WEWilliam K. Erly
    William K. Erly
  • BABoyd C. Ashdown
    Boyd C. Ashdown
  • RLRichard W. Lucio
    Richard W. Lucio
  • RCRaymond F. Carmody
    Raymond F. Carmody
  • JSJoachim F. Seeger
    Joachim F. Seeger
  • JAJennifer N. Alcala
    Jennifer N. Alcala
  • MBMaria J. Borja
    Maria J. Borja
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Abstract
The preoperative contrast enhanced CT and radionuclide brain scans of 60 patients with surgically verified supratentorial astrocytomas were evaluated and compared. Results indicated that the mechanisms of contrast enhancement and radionuclide uptake are identical in the detection of supratentorial gliomas. These diagnostic methods apparently mirror the integrity of the blood-brain barrier and therefore can be useful in assessing the degree of malignancy of supratentorial gliomas. However, lesions with an intact blood-brain barrier will be missed with radionuclide imaging. These parenchymal abnormalities and/or the associated mass effect will be detected with contrast enhanced computed tomography. These findings firmly establish contrast enhanced computed tomography. These findings firmly establish contrast enhanced CT as the primary investigate tool in the suspected brain tumor.