Elderly Patients and High Force Resistance Exercise—A Descriptive Report

Authors:
  • PMPaul McDonagh
    Paul McDonagh
  • DLDani Lipovic
    Dani Lipovic
  • PNPhyllis Napoles
    Phyllis Napoles
  • ABAmelia Bartholomew
    Amelia Bartholomew
  • KEKaryn Esser
    Karyn Esser
  • SLStan Lindstedt
    Stan Lindstedt
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Abstract
Abolic and muscle growth response. Methods: This is a descriptive study of 11 elderly individuals in rehabilitation who underwent a 2–3x/week high force resistance exercise that used eccentric contractions. Serum measures of muscle damage, inflammation, and an anabolic response are reported along with changes in muscle mass as measured with dual energy X-ray absorptiometry. Results: Negative work increased >3-fold during the 11 weeks of resistance exercise. There were no significant changes in the damage measure of serum creatine kinase (pretraining: 18.5 ± 1.2 Sigma units/ml; post-training: 19.2 ± 1.1 Sigma units/ml). Proinflammatory tumor necrosis factor-α values remained within normal range (<4.0 pg/ml) throughout the 11 weeks of training. A nonsignificant trend for an anabolic increase (65%) in insulin like growth factor-1 was noted along with a significant increase (6%) in thigh muscle mass. Conclusions: Neither damage, nor inflammation appear to be prerequisites for inducing anabolic and muscle growth responses in elderly individuals undergoing a high force resistance exercise with eccentric contractions....

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