EVI1 overexpression is a poor prognostic factor in pediatric patients with mixed lineage leukemia-AF9 rearranged acute myeloid leukemia
Open Access
- 11 July 2014
- journal article
- Published by Ferrata Storti Foundation (Haematologica) in Haematologica
- Vol. 99 (11) , e225-e227
Abstract
The ecotropic viral integration site-1 gene ( EVI1 ) encodes a zinc finger protein that functions as a transcriptional regulator of hematopoietic stem cell self-renewal and long-term multilineage repopulating activity.[1][1],[2][2] The mixed lineage leukemia gene (MLL ) rearrangements [i.e. t(11q23Keywords
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