rf testbed for thermoacoustic tomography

Thermoacoustic signal excitation is a function of intrinsic tissue properties and illuminating electric field. De-ionized (DI) water is a preferred acoustic coupling medium for thermoacoustics because acoustic and electromagnetic waves propagate in DI water with very little loss. We have designed a water-filled testbed propagating a controlled electric field with respect to pulse shape, power, and polarization. Directional coupler line sections permit measurement of incident, reflected, and transmitted powers. Both $S$ -parameters and $E_y$ measurement show that the electric-field distribution is relatively uniform in testbed. Comparing baseline power measurements to those taken with a test object in place yields power loss in the object, which should correlate to thermoacoustic signal strength. Moreover, power loss—and therefore thermoacoustic computerized tomography signal strength—is sensitive to the orientation of the object to the polarization of the electric field. This testbed will enable quantitative characterization of the thermoacoustic contrast mechanism in ex vivo tissue specimens.