Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2008–2010)
- 25 November 2010
- journal article
- review article
- Published by Wiley in Electrophoresis
- Vol. 32 (1) , 127-148
Abstract
Capillary electrophoresis has been alive for over two decades now; yet, its sensitivity is still regarded as being inferior to that of more traditional methods of separation such as HPLC. As such, it is unsurprising that overcoming this issue still generates much scientific interest. This review continues to update this series of reviews, first published in Electrophoresis in 2007, with an update published in 2009 and covers material published through to June 2010. It includes developments in the fields of stacking, covering all methods from field‐amplified sample stacking and large volume sample stacking, through to ITP, dynamic pH junction and sweeping. Attention is also given to on‐line or in‐line extraction methods that have been used for electrophoresis.Keywords
This publication has 261 references indexed in Scilit:
- Development of a membrane‐less dynamic field gradient focusing device for the separation of low‐molecular‐weight moleculesElectrophoresis, 2010
- Influence of the semi‐permeable membrane on the performance of dynamic field gradient focusingElectrophoresis, 2010
- Capillary zone electrophoresis with field enhanced sample stacking as a tool for targeted metabolome analysis of adenine nucleotides and coenzymes in Paracoccus denitrificansJournal of Separation Science, 2009
- Analysis of nerve agent degradation products in high‐conductivity matrices by transient ITP preconcentration and CZE separation coupled to ESI‐MSElectrophoresis, 2009
- Quantitative investigations on moving chelation boundary within a continuous EDTA‐based sample sweeping system in capillary electrophoresisElectrophoresis, 2008
- Electrokinetic sample injection for high‐sensitivity capillary zone electrophoresis (part 1): Effects of electrode configuration and settingElectrophoresis, 2008
- Immunoaffinity capillary electrophoresis as a powerful strategy for the quantification of low‐abundance biomarkers, drugs, and metabolites in biological matricesElectrophoresis, 2008
- Recent progress of online sample preconcentration techniques in microchip electrophoresisJournal of Separation Science, 2008
- On‐line stacking capillary electrophoresis for analysis of methotrexate and its eight metabolites in whole bloodElectrophoresis, 2008
- Sensitivity enhancement and second-dimensional information from solid phase extraction-capillary electrophoresis of entire high-performance liquid chromatography fractionsElectrophoresis, 1995