Quantitative interaction between the structures of organic compounds and their abilities to penetrate the blood-brain barrier
Authors:
- 1 June 2012
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Chemistry Journal
- Vol. 46 (3) , 133-138
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- A prediction model for blood–brain barrier permeation and analysis on its parameter biologicallyComputer Methods and Programs in Biomedicine, 2009
- QSAR Modeling of the Blood–Brain Barrier Permeability for Diverse Organic CompoundsPharmaceutical Research, 2008
- Benchmarking of QSAR Models for Blood-Brain Barrier PermeationJournal of Chemical Information and Modeling, 2007
- Predicting Penetration Across the Blood-Brain Barrier from Simple Descriptors and Fragmentation SchemesJournal of Chemical Information and Modeling, 2006
- Development of neuropeptide drugs that cross the blood-brain barrierNeuroRX, 2005
- Blood-Brain Barrier Permeation Models: Discriminating between Potential CNS and Non-CNS Drugs Including P-Glycoprotein SubstratesJournal of Chemical Information and Computer Sciences, 2004
- Empirical Relations Predicting Human and Rat Tissue:Air Partition Coefficients of Volatile Organic CompoundsToxicology and Applied Pharmacology, 2000
- Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settingsAdvanced Drug Delivery Reviews, 1997
- Estimation of Caco‐2 Cell Permeability using Calculated Molecular DescriptorsQuantitative Structure-Activity Relationships, 1996
- Blood—Brain Barrier: Transport Studies in Isolated Brain Capillaries and in Cultured Brain Endothelial Cells1991