STEROID-INDUCED SUPPRESSION OF GALLIUM UPTAKE IN TUMORS OF CENTRAL NERVOUS-SYSTEM - CONCISE COMMUNICATION

Authors:
  • AWA D Waxman
    A D Waxman
  • JBJ R Beldon
    J R Beldon
  • WRW Richli
    W Richli
  • DTD E Tanasescu
    D E Tanasescu
  • JSJ K Siemsen
    J K Siemsen
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  • 1 January 1978
    • journal article
    • research article
    • Vol. 19  (5) , 480-482
    • PMID:641569
Abstract
The effect of steroids given in greater than replacement doses on Ga and technetium glucoheptonate (TcGH] brain scans was evaluated by comparing the relative sensitivity of both radiopharmaceuticals in patients on and off steroids. A significant steroid effect on the sensitivity of 95% to 64% following steroids was shown. Steroids did not significantly alter the sensitivity of the TcGH study. The superiority of the TcGH brain scan over the gallium citrate brain scan in the steroid population suggests a difference in the uptake mechanism for the 2 radiopharmaceuticals.