Interactions of the EGFR juxtamembrane domain with PIP2-containing lipid bilayers: Insights from multiscale molecular dynamics simulations
Open Access
- 1 May 2015
- journal article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - General Subjects
- Vol. 1850 (5) , 1017-1025
Abstract
No abstract availableKeywords
Funding Information
- BBSRC (BB/G006911/1)
- Wellcome Trust (WT092970MA)
- The Yayasan Khazanah-OCIS Merdeka Scholarship Program
This publication has 41 references indexed in Scilit:
- Conformational Coupling across the Plasma Membrane in Activation of the EGF ReceptorCell, 2013
- Architecture and Membrane Interactions of the EGF ReceptorCell, 2013
- Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activationPflügers Archiv - European Journal of Physiology, 2010
- Cell Signaling by Receptor Tyrosine KinasesCell, 2010
- PIP2-Binding Site in Kir Channels: Definition by Multiscale Biomolecular SimulationsBiochemistry, 2009
- The Juxtamembrane Region of the EGF Receptor Functions as an Activation DomainMolecular Cell, 2009
- Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane SegmentCell, 2009
- An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor ReceptorCell, 2006
- GROMACS: Fast, flexible, and freeJournal of Computational Chemistry, 2005
- VMD: Visual molecular dynamicsJournal of Molecular Graphics, 1996