Valosin: isolation and characterization of a novel peptide from porcine intestine
Authors:
- 28 October 1985
- journal article
- Published by Wiley in FEBS Letters
- Vol. 191 (2) , 264-268
Abstract
The isolation and primary structure of a novel gastrointestinal peptide, designated valosin, is described. The peptide was purified from porcine upper gut extracts using an HPLC and N-terminal sequence screening strategy which depends on Chromatographic and structural characteristics as isolation criterion. The amino acid sequence of this peptide consists of 25 amino acid residues: V Q Y P V E H P D K F L K F G M T P S K G V L F Y.It does not show structural homology to known protein or nucleotide sequences. According to preliminary experiments, valosin possesses biological effects on the gastrointestinal tract of the dogKeywords
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