Adjudin disrupts spermatogenesis via the action of some unlikely partners
Authors:
Open Access
- 20 October 2011
- journal article
- Published by Taylor & Francis in Spermatogenesis
- Vol. 1 (4) , 291-297
Abstract
Adjudin, 1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide (formerly called AF-2364), is a potent analog of lonidamine [1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid] known to disrupt germ...Keywords
This publication has 57 references indexed in Scilit:
- Spermatogonial stem cells alone are not sufficient to re‐initiate spermatogenesis in the rat testis following adjudin‐induced infertilityInternational Journal of Andrology, 2011
- Adjudin-mediated Sertoli–germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivoThe International Journal of Biochemistry & Cell Biology, 2010
- Restricted Arp3 expression in the testis prevents blood–testis barrier disruption during junction restructuring at spermatogenesisProceedings of the National Academy of Sciences, 2010
- Cytoskeletal dynamics and spermatogenesisPhilosophical Transactions of the Royal Society B: Biological Sciences, 2010
- Intercellular Junction Assembly, Dynamics, and HomeostasisCold Spring Harbor Perspectives in Biology, 2009
- An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspectiveCritical Reviews in Biochemistry and Molecular Biology, 2009
- Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood‐testis barrier integrity in the seminiferous epitheliumThe FASEB Journal, 2009
- Chapter 7 Polarity Proteins and Cell–Cell Interactions in the Testis2009
- Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood–testis barrier restructuring during spermatogenesisProceedings of the National Academy of Sciences, 2008
- Ectoplasmic specialization: a friend or a foe of spermatogenesis?BioEssays, 2006