Tobakksrøyking og interaksjoner med legemidler
Authors:
- Espen MoldenEspen Molden
- Olav SpigsetOSOlav Spigset
Open Access
- 1 January 2009
- journal article
- abstracts
- Published by Norwegian Medical Association in Tidsskrift for Den norske legeforening
- Vol. 129 (7) , 632-633
Abstract
Tobacco smoking increases the turnover of many drugs due to induction of drug-metabolizing enzymes. Smokers therefore require higher doses of agents such as clozapine, olanzapine and theophylline than non- smokers. Enzyme induction declines after smoking cessation and without concomitant dose reduction there is an increased risk of adverse effects.Keywords
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