Comments on “Low-dose aspirin for preventing intrauterine growth restriction and pre-eclampsia in sickle cell pregnancy in Nigeria (PIPSICKLE): a randomised controlled trial”
Authors:
Open Access
- 15 January 2026
- journal article
- Published by PAGEPress Publications in Bleeding, Thrombosis and Vascular Biology
- Vol. 5 (1) , 1-8
Abstract
In the early 1970s, aspirin (acetylsalicylic acid) was shown to inhibit platelet aggregation by irreversibly acetylating platelet cyclooxygenase (COX), thereby suppressing the synthesis of its pro-aggregating product thromboxane A₂ (TxA₂)...Keywords
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