The Case for Cancer-Associated Fibroblasts: Essential Elements in Cancer Drug Discovery?
Open Access
- 30 March 2022
- journal article
- review article
- Published by Taylor & Francis in Future Drug Discovery
- Vol. 4 (1) , FDD71
Abstract
Although cancer-associated fibroblasts (CAFs) have gained increased attention for supporting cancer progression, current CAF-targeted therapeutic options are limited and failing in clinical trials.... Plain language summary Recent advances in cancer research have improved our understanding of disease progression; however, the number of drugs failing in clinical trials remains high and therefore,... Graphical abstract Incorporating emerging technologies in cancer drug discovery to improve translational impact.Keywords
Funding Information
- Oncopole (265878)
- Institute of Cancer Research (01871-000)
- Canada Research Chairs (Advanced Cellular Microenvironments)
- Canadian Cancer Society (706002)
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