Screening for BRCA1 and BRCA2 mutations in breast cancer patients from mexico: the public health perspective
Author:
Open Access
- 1 January 2009
- journal article
- Published by FapUNIFESP (SciELO) in Salud Pública de México
- Vol. 51, s191-s196
Abstract
Genetic testing for mutations in BRCA1 and BRCA2 has potentially important public health implications. Through judicious testing of women believed to be at high risk for early-onset breast cancer and for ovarian cancer, it is possible to identify highly-predisposed women prior to the development of cancer. Current preventive options include preventive mastectomy, preventive oophorectomy, tamoxifen and oral contraceptives. The ability to offer genetic testing in Mexico on a widespread level is enhanced if the common founder mutations in the two genes can be discovered or if the cost of genetic sequencing is reduced. It is important that a genetic testing service be a multi-disciplinary effort with co-ordinated follow-up.Keywords
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