Copper-Catalyzed γ-Sulfonylation of α,β-Unsaturated Carbonyl Compounds by Means of Silyl Dienol Ethers
Authors:
- 1 July 2015
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 17 (14) , 3572-3575
Abstract
A regioselective method for the introduction of sulfonyl groups at the γ-carbon of enone systems is reported. Using a copper catalyst and readily available sulfonyl chlorides, a range of silyl dienol ethers are sulfonylated in good yield under mild reaction conditions. The sulfone derivatives formed are poised for further synthetic manipulations as demonstrated by regioselective alkylations.Keywords
Funding Information
- Department of Chemistry, University of Illinois at Chicago
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