UPTAKE AND DISTRIBUTION OF RADIOACTIVE SELENIUM IN CATARACTOUS RAT LENS

Authors:
  • TSTR SHEARER
    TR SHEARER
  • RARS ANDERSON
    RS ANDERSON
  • JBJL BRITTON
    JL BRITTON
Google Scholar
  • 1 January 1983
    • journal article
    • research article
    • Vol. 2  (8) , 561-564
    • PMID:7184708
Abstract
A cataractous dose of sodium selenite tagged with 75Se was injected into 10-day-old rat pups. 75Se accumulated in the soluble and insoluble proteins of the lens. 75Se was not concentrated in the nuclear cataract. Interaction of Se with structural or enzymatic proteins of the lens may be an important step in the mechanism of selenite-induced cataract.