Involvement of USP24 in the DNA damage response
Authors:
Open Access
- 3 February 2015
- journal article
- opinion
- Published by Taylor & Francis in Molecular & Cellular Oncology
- Vol. 3 (1) , e1011888
Abstract
Deubiquitination has emerged as an important mechanism of regulating DNA repair pathways. We recently reported that USP24 is a novel p53 deubiquitinase that stabilizes p53 upon DNA damage. USP24 is upregulated by DNA damaging agents and plays an important role in maintaining genome stability.Keywords
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