Cardiac Surgery in the Parturient
Authors:
- Christopher R. CookCCChristopher R. Cook
- Charles D. CollardCCCharles D. Collard
- 1 March 2009
- journal article
- review article
- Published by Wolters Kluwer Health in Anesthesia & Analgesia
- Vol. 108 (3) , 777-785
Abstract
Heart disease is the primary cause of nonobstetric mortality in pregnancy, occurring in 1%-3% of pregnancies and accounting for 10%-15% of maternal deaths. Congenital heart disease has become more prevalent in women of childbearing age, representing an increasing percentage (up to 75%) of heart disease in pregnancy. Untreated maternal heart disease also places the fetus at risk. Independent predictors of neonatal complications include a maternal New York Heart Association heart failure classification >2, anticoagulation use during pregnancy, smoking, multiple gestation, and left heart obstruction. Because cardiac surgical morbidity and mortality in the parturient is higher than nonpregnant patients, most parturients with cardiac disease are first managed medically, with cardiac surgery being reserved when medical management fails. Risk factors for maternal mortality during cardiac surgery include the use of vasoactive drugs, age, type of surgery, reoperation, and maternal functional class. Risk factors for fetal mortality include maternal age >35 yr, functional class, reoperation, emergency surgery, type of myocardial protection, and anoxic time. Nonetheless, acceptable maternal and fetal perioperative mortality rates may be achieved through such measures as early preoperative detection of maternal cardiovascular decompensation, use of fetal monitoring, delivery of a viable fetus before the operation and scheduling surgery on an elective basis during the second trimester. Additionally, fetal morbidity may be reduced during cardiopulmonary bypass by optimizing maternal oxygen-carrying capacity and uterine blood flow. Current maternal bypass recommendations include: 1) maintaining the pump flow rate >2.5 L x min(-1) x m(-2) and perfusion pressure >70 mm Hg; 2) maintaining the hematocrit > 28%; 3) using normothermic perfusion when feasible; 4) using pulsatile flow; and 5) using alpha-stat pH management.Keywords
This publication has 43 references indexed in Scilit:
- Intensive care in obstetrics: An evidence-based reviewAmerican Journal of Obstetrics and Gynecology, 2006
- Anesthesia in pregnant patients for nonobstetric surgeryJournal of Clinical Anesthesia, 2006
- European Resuscitation Council Guidelines for Resuscitation 2005Resuscitation, 2005
- Anticoagulation with low‐molecular‐weight heparin during pregnancyInternational Journal of Gynecology & Obstetrics, 1999
- Fetal and maternal hemodynamic and metabolic effects of maternal nitroglycerin infusions in sheepAmerican Journal of Obstetrics and Gynecology, 1997
- CorrespondenceThe Annals of Thoracic Surgery, 1997
- Long-term outcome after heart transplantation for peripartum cardiomyopathyAmerican Heart Journal, 1994
- Maternal Esmolol Administration Resulting in Fetal Distress and Cesarean Section in a Term PregnancyAnesthesiology, 1992
- Incidence of Venous Air Embolism during Epidural Catheter InsertionAnesthesiology, 1982
- Natural Course of Peripartum CardiomyopathyCirculation, 1971