Use of Protein Cages as a Template for Confined Synthesis of Inorganic and Organic Nanoparticles
- 19 October 2014
- book chapter
- Published by Springer Nature
- Vol. 1252, 17-25
Abstract
Protein cages are hollow spherical proteins assembled from a defined number of subunits. Because they are extremely homogeneous in size and structure, their interior cavities can serve as ideal templates to encapsulate and synthesize well-defined nanoparticles. Here, we describe the exemplary synthesis of a hard and a soft material in two representative protein cages, i.e., magnetite nanoparticles in ferritin and a poly(2-aminoethyl)methacrylate inside a viral capsid derived from the bacteriophage P22.Keywords
This publication has 17 references indexed in Scilit:
- Use of the interior cavity of the P22 capsid for site-specific initiation of atom-transfer radical polymerization with high-density cargo loadingNature Chemistry, 2012
- Using Synthetically Modified Proteins to Make New MaterialsAccounts of Chemical Research, 2011
- Viruses and Nanotechnology2009
- A human ferritin iron oxide nano‐composite magnetic resonance contrast agentMagnetic Resonance in Medicine, 2008
- Biological Containers: Protein Cages as Multifunctional NanoplatformsAdvanced Materials, 2007
- Targeting of Cancer Cells with Ferrimagnetic Ferritin Cage NanoparticlesJournal of the American Chemical Society, 2006
- Viruses: Making Friends with Old FoesScience, 2006
- Host–guest encapsulation of materials by assembled virus protein cagesNature, 1998
- The ferritins: molecular properties, iron storage function and cellular regulationBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1996
- Synthesis of inorganic nanophase materials in supramolecular protein cagesNature, 1991