Simple and objective method for routine detection of the macular pigment xanthophyll

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Abstract
Age-related macular degeneration (AMD) is the leading source for legal blindness in the elderly population in the western world.1 Despite intensive research, its molecular pathophysiology remains inadequately understood.2 It is commonly assumed that the accumulation of lipofuscin in the retinal pigment epithelium (RPE) and the formation of drusen at Bruch's membrane play an important role in the development of AMD.

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