Preparation of ethyl 5(s),6-epoxy-3(r)-(methoxymethoxy)hexanoate: a key chiral intermediate for mevinolin and compactin.

This publication has 27 references indexed in Scilit:

• Total synthesis of (+)-dihydrocompactin
  Journal of the American Chemical Society, 1984
• Reductive transformation and cyclopropanation of mevinolin (6.alpha.-methylcompactin). Generation of chirality in the 1,4-hydrostannation of a cyclic diene
  The Journal of Organic Chemistry, 1983
• Total synthesis of the hypocholesterolemic agent compactin
  Journal of the American Chemical Society, 1983
• Structural modification of mevinolin
  The Journal of Organic Chemistry, 1982
• Incorporation of 2(S)‐methylbutanoic acid‐1‐¹⁴C into the structure of mevinolin
  Journal of Labelled Compounds and Radiopharmaceuticals, 1982
• Methyl 3-0-benzyl-2,4,6-trideoxy-6-iodo-α-d--hexopyranoside, a chiral synthon for the synthesis of inhibitors of HMG-CoA reductase
  Tetrahedron Letters, 1982
• Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.
  Proceedings of the National Academy of Sciences, 1980
• Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.
  The Journal of Antibiotics, 1979
• Regulation of HMG-CoA Reductase
  1976
• ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.
  The Journal of Antibiotics, 1976