Frequent Loss of Heterozygosity at the 19p13.3 Locus Without LKB1/STK11 Mutations in Human Carcinoma Metastases to the Brain

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Abstract
Inactivating germline mutations of the novel putative tumor-suppressor gene LKB1/STK11at 19p13.3 have been shown to cause Peutz-Jeghers syndrome (PJS), an autosomal dominantly inherited disease...