Mutational Analysis of the TolA C-Terminal Domain ofEscherichia coliand Genetic Evidence for an Interaction between TolA and TolB
- 15 August 2002
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 184 (16) , 4620-4625
Abstract
The Tol proteins are involved in the outer membrane stability of gram-negative bacteria. The C-terminal domain of TolA was mutagenized to identify residues important for its functions. The isolation of suppressor mutants of tolA mutations in the tolB gene confirmed an interaction between TolAIII and the N-terminal domain of TolB.Keywords
This publication has 32 references indexed in Scilit:
- Salmonella enterica Serovar Typhimurium Resistance to Bile: Identification and Characterization of the tolQRA ClusterJournal of Bacteriology, 2002
- Pal Lipoprotein ofEscherichia coliPlays a Major Role in Outer Membrane IntegrityJournal of Bacteriology, 2002
- Energy-Dependent Conformational Change in the TolA Protein ofEscherichia coliInvolves Its N-Terminal Domain, TolQ, and TolRJournal of Bacteriology, 2001
- TolB protein ofEscherichia coliK‐12 interacts with the outer membrane peptidoglycan‐associated proteins Pal, Lpp and OmpAMolecular Microbiology, 1998
- Proposal for a peptidoglycan‐associating alpha‐helical motif in the C‐terminal regions of some bacterial cell‐surface proteinsMolecular Microbiology, 1995
- Protein Complex within Escherichia coli Inner MembraneJournal of Biological Chemistry, 1995
- Transmembrane α-Helix Interactions are Required for the Functional Assembly of theEscherichia coliTol ComplexJournal of Molecular Biology, 1995
- The excC gene of Escherichia coli K‐12 required for cell envelope integrity encodes the peptidoglycan‐associated lipoprotein (PAL)Molecular Microbiology, 1992
- The tol gene products and the import of macronmolecules into Escherichia coliMolecular Microbiology, 1991
- Expression Using the T7 RNA Polymerase/Promoter SystemCurrent Protocols in Molecular Biology, 1990