Chromone derivatives, R- and S- taeniolin, from the marine-derived fungus Taeniolella sp. BCC31839

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Abstract
Two unknown enantiomeric compounds, named (R)- and (S)-taeniolin, along with six known compounds, were isolated from the marine-associated fungus Taeniolella sp. BCC31839. Chemical structures were determined by NMR spectroscopic techniques, and the absolute configurations were confirmed by Mosher application together with CD spectral analyses. Both were inactive for antimicrobial activity against multidrug-resistant malaria parasite (Plasmodium falciparum) and bacteria (Mycobacerium tuberculosis and Bacillus cereus) at maximum tested concentration.
Funding Information
  • The Thailand Research Fund (RSA5980001, RSA6280019)
  • the National Center for Genetic Engineering and Biotechnology (P19-50917)

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