Assaying phenothiazine derivatives as trypanothione reductase and glutathione reductase inhibitors by theoretical docking and Molecular Dynamics studies

This publication has 64 references indexed in Scilit:

• Trypanosoma cruzitargets for new chemotherapeutic approaches
  Expert Opinion on Therapeutic Targets, 2008
• The Parasite-Specific Trypanothione Metabolism of Trypanosoma and Leishmania
  Biological Chemistry, 2003
• A Critical Review on Chagas Disease Chemotherapy
  Memórias do Instituto Oswaldo Cruz, 2002
• Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress
  Molecular Microbiology, 2000
• Evidence that trypanothione reductase is an essential enzyme in Leishmania by targeted replacement of the tryA gene locus
  Molecular Microbiology, 1998
• Down-regulation of Leishmania donovani trypanothione reductase by heterologous expression of a trans-dominant mutant homologue: Effect on parasite intracellular survival
  Proceedings of the National Academy of Sciences, 1998
• Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages
  The EMBO Journal, 1997
• A Unique Cascade of Oxidoreductases Catalyses Trypanothione-Mediated Peroxide Metabolism in Crithidia fasciculata
  Biological Chemistry, 1997
• The challenge of Chagas' disease chemotherapy: An update of drugs assayed against Trypanosoma cruzi
  Acta Tropica, 1993
• Novel biochemical pathways in parasitic protozoa
  Parasitology, 1989