Prevention of Depression in At-Risk Adolescents

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Abstract
Depression is a common, chronic, and impairing disorder with first onset often occurring during adolescence1 and affecting close to a quarter of all adults during their lifetime.2 The World Health Organization3 estimates that depression is the third leading cause of global disease, is projected to be the second leading cause by 2020, and will rank first in high-income countries by 2030.4 Thus, depression is a major public health problem that requires the development, implementation, and evaluation of strategies for preventing its onset and recurrence.

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