Hyposlenism After Splenectomy
Open Access
- 28 September 2015
- journal article
- abstracts
- Published by Paediatrician Publishers LLC in Annals of the Russian academy of medical sciences
- Vol. 70 (4) , 413-418
Abstract
Splenectomy is a serious operation, which includes the removal of the largest peripheral immune organ. Vast array of different pools of immunocompetent cells and immune-factors eliminate from the body as a result of this operation. Occurrence of hyposplenism in our country pediatric service is not determined — there are neither clear criteria for its diagnosis, nor approved algorithms for prevention. Data of postsplenectomy sepsis incidence in Russia are unknown. In this review article authors give contemporary literature data relating to the issue of developing hyposplenism and changes in the body after removal of spleen. Systemic effect of organ-resecting operation and the basic directions of overwhelming post-splenectomy infection and sepsis prevention are discussed.Keywords
This publication has 25 references indexed in Scilit:
- Laparoscopic splenectomy for medically refractory immune thrombocytopenia (ITP): A retrospective cohort study on longtime response predicting factors based on consensus criteriaInternational Journal of Surgery, 2014
- Post-splenectomy and hyposplenic statesThe Lancet, 2011
- Hereditary spherocytosis and partial splenectomy in children: review of surgical technique and the role of imagingPediatric Radiology, 2010
- Laparoscopic splenectomy for solitary splenic tumorsSurgical Endoscopy, 2008
- Laparoscopic Partial Splenectomy: Indications and results of a multicenter retrospective studySurgical Endoscopy, 2007
- Laparoscopic splenectomy for lymphoproliferative diseaseSurgical Endoscopy, 2004
- Asplenic-hyposplenic Overwhelming Sepsis: Postsplenectomy Sepsis RevisitedPediatric and Developmental Pathology, 2001
- Immunological Consequences of Splenectomy1985
- Preservation of splenic tissue prevents postsplenectomy pulmonary sepsis following bacterial challengeJournal of Surgical Research, 1982
- Partial splenectomy and overwhelming infection in ratsJournal of Surgical Research, 1982