Parakeratotic horns in a patient with myeloma
Authors:
- 1 February 1987
- journal article
- research article
- Published by Wiley in Journal of Cutaneous Pathology
- Vol. 14 (1) , 54-58
Abstract
We describe a patient who in association with myeloma developed generalized keratotic horns. Light microscopy revealed parakeratotie plugs resembling those seen in Kyrle's disease. Electron microscopy showed distortion of keratinosomes and laminated bodies indicating a profund disturbance in keratinization. A strong C3 and weaker IgG and IgA immunofluoresence were seen in the areas of epidermal plugs and horns but no circulating epidermal antibodies were detected. All symptoms disappeared when therapy for myeloma was started favoring that (hey were of paraneoplastic origin.Keywords
This publication has 11 references indexed in Scilit:
- Kyrle's disease and hepatic insufficiencyArchives of Dermatology, 1986
- Follicular Hyperkeratosis and Cryocrystalglobulinemia SyndromeArchives of Dermatology, 1985
- Follicular hyperkeratosis and cryocrystalglobulinemia syndrome. Occurrence in a patient with multiple myelomaArchives of Dermatology, 1985
- Immunoglobulin deposits in bladder epithelium and vessels in interstitial cystitis: Possible relationship to circulating anti-intermediate filament autoantibodiesClinical Immunology and Immunopathology, 1984
- The perforating disordersJournal of the American Academy of Dermatology, 1984
- In Vitro Complement Binding in Human Skin Cells with Altered DifferentiationJournal of Investigative Dermatology, 1983
- Kyrle's Disease in Patients With Chronic Renal FailureArchives of Dermatology, 1982
- Kyrle's disease in patients with chronic renal failureArchives of Dermatology, 1982
- Kyrle's DiseaseArchives of Dermatology, 1968
- Kyrle's disease. I. Clinical findings in five cases and review of literatureArchives of Dermatology, 1968