Germline-Activating RRAS2 Mutations Cause Noonan Syndrome

This publication has 32 references indexed in Scilit:

• Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells
  Disease Models & Mechanisms, 2009
• The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders
  Human Mutation, 2008
• Shp2 Knockdown and Noonan/LEOPARD Mutant Shp2–Induced Gastrulation Defects
  PLOS Genetics, 2007
• Noonan syndrome
  Orphanet Journal of Rare Diseases, 2007
• Germline Mutations in Genes Within the MAPK Pathway Cause Cardio-facio-cutaneous Syndrome
  Science, 2006
• Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome
  Nature Genetics, 2006
• Germline KRAS mutations cause Noonan syndrome
  Nature Genetics, 2006
• Germline mutations in HRAS proto-oncogene cause Costello syndrome
  Nature Genetics, 2005
• TC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-κB signaling pathway
  Oncogene, 2002
• Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
  Nature Genetics, 2001