Synthesis of novel S - and O -disaccharide analogs of heparan sulfate for heparanase inhibition
- 1 April 2022
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic & Biomolecular Chemistry
- Vol. 20 (17) , 3528-3534
Abstract
Design and synthesis of the first sulfated thiodisaccharide, analog of a heparane sulfate sequence, which is able to inhibit heparanase with an IC 50 in the micromolar range.Keywords
Funding Information
- Région Hauts-de-France (2019.01203/8)
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