The Influence of Fillers on the Structure of Siloxane Films

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Abstract
The influence of fillers on the structures of siloxane films is studied. Three versions of fillers are considered: ethyl alcohol, chitosan, and sodium bicarbonate with its subsequent removal. It is shown that the use of alcohol leads to a change in the surface structure and formation of numerous “pit” pores. The use of sodium bicarbonate or chitosan as fillers makes it possible to create developed networks of pores intersecting with each other and having access to the surface. The possibility of controlling the thickness of porous layers by varying the concentration of the introduced filler is shown. A conclusion is drawn that the studied versions of modification of the structure of siloxane films open up wide opportunities for creating drug delivery systems or other active agents, including those with controlled prolonged action.

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