Supplementary Table 4 from Low TCR Binding Strength Results in Increased Progenitor-like CD8+ Tumor-Infiltrating Lymphocytes

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Abstract
Negative Altered cytoskeletal gene expression Actg1, Tuba1b, Tubb4b Supplemental Table 1: Cluster identity determined by transcriptional differences between each cluster. Each cluster was given a brief description based on the genes that were the most significantly upregulated (or downregulated where noted) relative to either other tetramer-positive or tetramer-negative clusters. Purple clusters are predominantly tetramer-positive, blue clusters are a mix of tetramer-positive and tetramer-negative cells and gray clusters are predominantly tetramer-negative cells. Clusters are numbered based on the number of cells occupying each cluster, with cluster 0 having the most cells and cluster 13 the least. Tetramer binding was based on if cells within the cluster came predominantly from a tetramer-positive or tetramer-negative library, the majority of clusters had minimal mixing of these groups. 1.

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