Beyond the binary: a nationwide study of physician decision orientations toward artificial hydration in terminal cancer care
Open Access
- 22 June 2026
- journal article
- Published by Oxford University Press (OUP) in The Oncologist
- Vol. 31 (8)
Abstract
Background: Artificial hydration (AH) in terminally ill cancer patients remains ethically and clinically controversial. Although evidence suggests limited benefit near the end of life, AH is frequently administered, particularly in East Asian settings where it may carry symbolic meaning. This study conceptualized physician decision-making as a clinical spectrum and examined demographic, clinical, and ethical factors associated with AH decision orientations. Materials and Methods: A nationwide cross-sectional survey of palliative care–trained physicians in Taiwan assessed clinical practices and ethical domains (autonomy, beneficence, non-maleficence, justice, cultural, and emotional factors). Scenario-based scores were used to derive continuation, withdrawal, and variability indices. Two-step cluster analysis identified decision-orientation profiles. Group differences were analyzed using ANOVA, chi-square tests, and multinomial logistic regression. Results: Among 377 respondents, 4 decision-orientation clusters emerged: contextual/proportional, selective continuation, conservative/continuation-leaning balancing, and consistent withdrawal. Several demographic and professional characteristics differed across clusters. Ethical domains also differed significantly. Multinomial regression showed that cultural and emotional factors were associated with contextual/proportional orientation, whereas beneficence independently predicted selective continuation orientation. Hydration volume and consideration of life expectancy differed across clusters, supporting behavioral distinctions among decision orientations. Conclusion: AH decision-making reflects multiple context-sensitive physician orientations shaped by both ethical considerations and professional characteristics, rather than a binary continuation–withdrawal model.Keywords
Funding Information
- Ministry of Science and Technology
- National Science and Technology Council (112-2314-B-002-103-MY3)
- National Science and Technology Council (114-2314-B-037-059)
This publication has 45 references indexed in Scilit:
- Use of artificial hydration in patients diagnosed with senility as the cause of death by home care physicians: A cross₋sectional studyJournal of General and Family Medicine, 2024
- Association between the amount of artificial hydration and quality of dying among terminally ill patients with cancer: The East Asian Collaborative Cross‐Cultural Study to Elucidate the Dying ProcessCancer, 2022
- Care of the adult cancer patient at the end of life: ESMO Clinical Practice GuidelinesESMO Open, 2021
- Continuing, Withdrawing, and Withholding Medical Treatment at the End of Life and Associated Characteristics: a Mortality Follow-back StudyJournal of General Internal Medicine, 2019
- ESPEN guideline on ethical aspects of artificial nutrition and hydrationClinical Nutrition, 2016
- Practice Patterns and Perceptions About Parenteral Hydration in the Last Weeks of Life: A Survey of Palliative Care Physicians in Latin AmericaJournal of Pain and Symptom Management, 2012
- Artificial nutrition and hydration at the end of life: Ethics and evidencePalliative and Supportive Care, 2006
- Artificial Hydration Therapy, Laboratory Findings, and Fluid Balance in Terminally Ill Patients with Abdominal MalignanciesJournal of Pain and Symptom Management, 2006
- Terminal cancer patients' wishes and influencing factors toward the provision of artificial nutrition and hydration in TaiwanJournal of Pain and Symptom Management, 2004
- Agitated Terminal Delirium and Association with Partial Opioid Substitution and HydrationJournal of Palliative Medicine, 2003