A Guide to the Perplexed on the Specificity of Antibodies
- 15 September 2008
- journal article
- review article
- Published by SAGE Publications in Journal of Histochemistry & Cytochemistry
- Vol. 57 (1) , 1-5
Abstract
Many investigators are unaware of the potential problems with specificity of antibodies and the need to document antibody characterization meticulously for each antibody that is used. In this review, I consider the principles of antibody action and how they define a set of rules for what information should be obtained by the investigator before using an antibody in a serious scientific investigation.Keywords
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