Alpha 1-antitrypsin deficiency and infantile liver disease.
Authors:
- J L McPhieJMJ L McPhie
- S BinnieSBS Binnie
- P W BruntPBP W Brunt
Open Access
- 1 August 1976
- journal article
- case report
- Published by BMJ in Archives of Disease in Childhood
- Vol. 51 (8) , 584-588
Abstract
Infantile liver disease with deficiency of serum alpha1-antitrypsin is illustrated by a description of the clinical, biochemical, and pathological findings in two affected families. The simplicity of the diagnostic tests is emphasized. Review of 61 biopsies of liver from children and adolescents provided a further 3 cases. It is prudent to exclude this metabolic defect in children with a history of "neonatal hepatitis".Keywords
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