Central Dopaminergic Pathways in Hemiparkinsonism Examined by Positron Emission Tomography
Authors:
- E.S. GarnettEGE.S. Garnett
Open Access
- 1 February 1984
- journal article
- research article
- Published by Cambridge University Press (CUP) in Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
- Vol. 11 (S1) , 174-179
Abstract
[18F] 6-fluoro-L-dopa and positron emission tomography has been used to study intracerebral dopamine distribution in five control subjects and six patients with hemiparkinsonism. In the control subjects striatal, frontal and cingulate accumulations were clearly seen. In addition 18F concentrated in the region of the insula and the parietal lobe.Keywords
This publication has 8 references indexed in Scilit:
- Performance Characteristics of the McMaster Positron Emission TomographIEEE Transactions on Nuclear Science, 1984
- Striatal dopamine metabolism in living monkeys examined by positron emission tomographyBrain Research, 1983
- Dopamine visualized in the basal ganglia of living manNature, 1983
- Metabolic effects of unilateral lesion of the substantia nigraJournal of Neuroscience, 1981
- Receptor basis for dopaminergic supersensitivity in Parkinson's diseaseNature, 1978
- [18F] fluoro-dopa: A unique gamma emitting substrate for Dopa decarboxylaseCellular and Molecular Life Sciences, 1975
- Determination of homovanillic acid turnover in rat striatum using a monoamine oxidase inhibitorEuropean Journal of Pharmacology, 1973
- OCCURRENCE AND DISTRIBUTION OF AROMATIC l‐AMINO ACID (l‐DOPA) DECARBOXYLASE IN THE HUMAN BRAINJournal of Neurochemistry, 1972