GROUP-SPECIFIC HUMAN GRANULOCYTE ANTIGENS ON A CHRONIC MYELOGENOUS LEUKEMIA CELL LINE WITH A PHILADELPHIA CHROMOSOME MARKER

Authors:
  • SDS I Drew
    S I Drew
  • PTP I Terasaki
    P I Terasaki
  • RBR J Billing
    R J Billing
  • OBO J Bergh
    O J Bergh
  • JMJ Minowada
    J Minowada
  • EKE Klein
    E Klein
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  • 1 January 1977
    • journal article
    • research article
    • Vol. 49  (5) , 715-718
    • PMID:66956
Abstract
Group specific human granulocyte antigens are serologically detectable with granulocytotoxic positive human alloantisera on a cell line, K562, of chronic myelogenous leukemia origin which bears a Philadelphia chromosomal marker. The same cell line lacks serologically detectable HLA, B2 microglobulin, and B [bone marrow-derived]-lymphocyte antigens. Granulocyte antigens are important cell markers for cell lines of suspected myeloid lineage.