A Domino Diels–Alder Approach toward the Tetracyclic Nicandrenone Framework
- 2 November 2015
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 17 (22) , 5517-5519
Abstract
The tetracarbocyclic framework of the nicandrenone natural products is formed in one step from a linear precursor via a domino intramolecular Diels–Alder/intramolecular furan Diels–Alder/aromatization sequence. The approach represents a new 0 → ABCD strategy for the preparation of aromatic steroids.Keywords
Funding Information
- Department of Industry, Innovation, Science, Research and Tertiary Education, Australian Government
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